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Stem cells are specialized cells with the ability to support the body’s natural repair and signaling processes. In regenerative medicine, mesenchymal stem cells (MSCs) are widely studied for their role in cellular communication, immune modulation, and tissue support.
Scientific and clinical research continues to explore how MSCs interact with surrounding cells through signaling pathways, growth factors, and extracellular vesicles.
At ZignaGenix, we work with Wharton’s Jelly–derived mesenchymal stem cells (WJ-MSCs), including our proprietary Infinity Hypoxic Live Stem Cells™, cultivated under controlled laboratory conditions.
These cells are selected and prepared with careful attention to sourcing, handling, and growth practices to support consistency and cellular integrity throughout the preparation process.
Allogeneic MSCs are derived from screened donors and prepared for use without requiring a patient’s own cells. This approach allows for standardized preparation methods and consistent quality controls across batches.
All protocols are designed with patient safety, regulatory awareness, and responsible laboratory practices in mind.
Although donors are screened for health issues, the cells extracted from umbilical cords are then tested for specific proteins and genes that research has identified offer high potential for effective treatment.
Cells that pass screening tests are purified and expanded so that therapy can be prepared that contains millions of high-potency cells that the body can use to promote healing, modulate the immune system, and reduce inflammation.
Cells are tested as they are expanded and “passaged” into larger containers. Once expansion is complete, cells are tested again to verify that they meet various markers and criteria for purity and potency.
After cells have been expanded and tested, they are frozen in our cell bank. When reactivated, they are tested once more to ensure quality and viability.
Rather than replacing damaged tissue directly, MSCs are studied for how they communicate with surrounding cells. This includes signaling that may support immune balance, inflammation response, and tissue environment regulation.
Research continues to examine how these cellular interactions may contribute to broader regenerative processes.
Cell quality depends on how cells are grown, handled, and maintained — not just where they come from.
These factors help preserve cell integrity, signaling behavior, and consistency.
Passage refers to how many times cells are transferred during growth. Early passage cells are handled fewer times, helping preserve their original structure and behavior.
Limiting passages helps maintain the cells’ original structure and behavior.
Generation refers to how many times a cell has divided during growth.
Even at the same passage level, cells can differ in biological age depending on how aggressively they were expanded.
Expansion increases cell quantity to usable levels while maintaining cellular stability. Responsible expansion avoids unnecessary stress and prioritizes consistency over volume.
Adequate cell
yield without over-forcing growth
Avoiding unnecessary cellular stress
Preserving natural cell behavior
Rather than prioritizing speed or volume, our protocols emphasize controlled growth and respect for cellular biology throughout the process.
This philosophy helps differentiate responsible cell preparation from volume-driven claims often seen elsewhere.
Our process is designed to ensure patients speak with trained professionals at the appropriate stage of their journey. This allows for focused consultations, clear communication, and a more streamlined experience from inquiry to care coordination.
• Zigna Genix Treatment Protocols
• Degenerative Disc Disease
• Knee Osteoarthritis
• Shoulder & Elbow Overuse Injuries
• Spinal Cord Injuries
• Tendinopathies
• Erectile Dysfunction
• Regular follow-up: patients not included in research protocols
• Research follow-up; patients included in search protocols
• Specific follow-up period for each protocol
• Patient educational interventions
• Zigna Genix Treatment Protocols
• Degenerative Disc Disease
• Knee Osteoarthritis
• Shoulder & Elbow Overuse Injuries
• Spinal Cord Injuries
• Tendinopathies
• Erectile Dysfunction
• COVID 19
• Spinal Cord Injury
• Concussion
Design and assembly of laboratory experiments and tests, original articles, reviews, and short articles
Information analysis for knowledge generation, management reports for decision-making and other institutional reports, infographics, and other marketing materials
Clinical trials, observational research, protocols, case series, and case reports
Systematic literature reviews, evidence synthesis for clinical management decision making, creation, adoption, and adaptation of clinical practice guidelines, and management guidelines by consensus of experts
BioXscience, a subsidiary of Zigna Genix, is responsible for planning and executing our research and innovation activities aimed at identifying specific knowledge gaps in the field of regenerative medicine.
The BioXscience team develops and publishes meta-analyses and systematic reviews to combine peer-reviewed literature, case studies, and observational data in the creation of best practice, patient-specific protocols that include MSC therapy with complementary therapies. Together, optimal patient outcomes are achieved with improvements in pain, function, and quality of life.
Our care protocols are informed by existing scientific literature and commonly accepted laboratory practices, with an emphasis on responsible application and continuous evaluation.
Our approach to healthcare is distinguished by evidence-based care protocols meticulously designed to address various medical conditions.
ZignaGenix continues to explore educational initiatives, scientific publications, and collaborative research efforts to contribute to broader understanding in regenerative medicine.
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