Some species of gut-dwelling bacteria activate nerves in the gut to promote the desire to exercise, according to a study in mice that was led by researchers at the Perelman School of Medicine at the University of Pennsylvania. The study was published today in Nature, and reveals the gut-to-brain pathway that explains why some bacteria […]
Sleep behaviors are associated with an increased risk of developing metabolic-dysfunction associated fatty liver disease (MAFLD), shows a Chinese analysis that suggests the effect may be independent of obesity. Late bedtimes, snoring, and prolonged daytime napping were significantly associated with MAFLD, increasing the risk by 37%, 59%, and 17%, respectively, whereas people with both poor […]
Maintaining an adequate quantity and quality of skeletal muscle is important for health and functionality across the lifespan given its integral role in the regulation of postprandial glycemia and lipidemia, conversion of chemical energy to mechanical work, and contribution to whole body energy flux. Prolonged periods of sitting are common in many workplace environments and […]
Maternal and paternal exercise are well-established to improve the metabolic health of adult offspring. Tissue and serum metabolites play a fundamental role in the health of an organism, but how parental exercise affects offspring tissue and serum metabolites has not yet been investigated. Metabolites are substances made or used when the body breaks down food, […]
Approximately one third of human life is devoted to sleep, emphasizing the vital role of sleep in several physiological functions essential for health. There is also consistent evidence of an association of sleep duration with chronic diseases, such as cardiovascular disease (CVD) and cancer, and with mortality, although there remain a number of outstanding questions […]
Multiple Sclerosis (MS) is a chronic inflammatory, autoimmune, and neurodegenerative disease of the central nervous system (CNS). MS affects approximately 2.5 million people worldwide. High prevalence of MS is seen in northern parts of Europe and North America. Multiple sclerosis (MS) is a potentially disabling disease of the brain and spinal cord (central nervous system). […]
Colorectal cancer is the third most commonly diagnosed malignancy among both men and women in the United States and the second leading cause of death from cancer worldwide. Diet has been recognized as an important modifiable risk factor for colorectal cancer. Meanwhile, ultra-processed foods (that is, industrial ready-to-eat or ready-to-heat formulations made of little or […]
A recently published WHO report revealed that noncommunicable diseases (NCDs), such as cardio- and cerebral diseases, cancers, endocrine/metabolic diseases, including type 2 diabetes and obesity, account for 38 million deaths worldwide. Moreover the WHO predicts an increase in mortality caused by NCDs to 52 million in 2030. Fast progress of those impairments is mostly associated […]
Low-grade systemic inflammation is associated with an increased risk of various diseases, including cardiovascular disease (CVD) and cancer. Modifiable factors can reduce inflammation and potentially modulate disease risk. One of these factors is dietary fiber intake, in which higher intakes have been associated with lower systemic inflammation in various studies, in both healthy adults and […]
Diabetes is a major global health concern, affecting mortality rates and the quality of life of those with the condition and their families. There were an estimated 463 million people with diabetes in the world in 2019, of whom 90% to 95% have type 2 diabetes. By 2045, it is estimated that there will be […]