Multiple Sclerosis (MS) is a chronic inflammatory, autoimmune, and neurodegenerative disease of the central nervous system (CNS). MS affects approximately 2.5 million people worldwide. High prevalence of MS is seen in northern parts of Europe and North America. Multiple sclerosis (MS) is a potentially disabling disease of the brain and spinal cord (central nervous system). […]
Some species of gut-dwelling bacteria activate nerves in the gut to promote the desire to exercise, according to a study in mice that was led by researchers at the Perelman School of Medicine at the University of Pennsylvania. The study was published today in Nature, and reveals the gut-to-brain pathway that explains why some bacteria […]
Finding and implementing preventive measures that can slow down the aging process is currently recognized as a major challenge of preventive medicine to combat the epidemic of age-dependent chronic diseases that is emerging as a result of a rapidly aging world population. Disparities in the pace of biological aging are already detectable at midlife indicating […]
Sudden cardiac arrest, occurring in the setting of impaired cardiac function and structural heart disease that lead to ventricular tachycardia (VT) and ventricular fibrillation, is a leading cause of death in the world. Implantable cardioverter defibrillators improve survival in at-risk populations at the cost of reduced quality of life from shocks and potential for worsening […]
Florida State University College of Medicine researchers have linked aspartame, an artificial sweetener found in nearly 5,000 diet foods and drinks, to anxiety-like behavior in mice. Along with producing anxiety in the mice who consumed aspartame, the effects extended up to two generations from the males exposed to the sweetener. The study is published in […]
In recent decades, the prevalence of type 2 diabetes has increased dramatically. We refer to insulin sensitivity, insulin secretion, and insulin clearance as components of “insulin homeostasis,” given that these traits encompass action, production, and removal of insulin. Dysfunction in insulin sensitivity and insulin secretion underlie the development of type 2 diabetes. The role of […]
Obesity is a worldwide epidemic that predisposes individuals to many age-associated diseases, but its exact effects on organ dysfunction are largely unknown. Hair follicles—mini-epithelial organs that grow hair—are miniaturized by aging to cause hair loss through the depletion of hair follicle stem cells (HFSCs). Normally, HFSCs self-renew every hair follicle cycle. This is part of […]
People who eat or drink more foods with antioxidant flavonols, which are found in several fruits and vegetables as well as tea and wine, may have a slower rate of memory decline, according to a study published in the November 22, 2022, online issue of Neurology®, the medical journal of the American Academy of Neurology. […]
Sleep behaviors are associated with an increased risk of developing metabolic-dysfunction associated fatty liver disease (MAFLD), shows a Chinese analysis that suggests the effect may be independent of obesity. Late bedtimes, snoring, and prolonged daytime napping were significantly associated with MAFLD, increasing the risk by 37%, 59%, and 17%, respectively, whereas people with both poor […]
As medicine shifts its focus towards sustainable lifestyle changes to combat disease, diet is often the first criteria to be evaluated since its composition influences the health status of an individual. For example, a Western diet consisting primarily of saturated fats that contribute to the increasing levels of obesity, diabetes, and comorbidities in Western countries. […]